Consensus-based statements for the management of mitochondrial stroke-like episodes
نویسندگان
چکیده
منابع مشابه
Mitochondrial encephalopathy, lactic acidosis, and stroke-like episodes (MELAS).
We report the clinical, pathological, and genetic findings of a case of MELAS syndrome. This was a man who died for metabolic failure at the age of 27 years. His familiar history was positive for hypoacusia and stroke. He was of short stature and presented mild mental retardation. Since the age of 21 he suffered from recurrent brain-ischemic lesions mainly in the occipital lobes, documented by ...
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A 9 years old boy suffered from recurrent headache, nausea and blurred vision for 2 months. His medical history revealed failure to thrive, easy constipation and exercise intolerance for more than two years. Initial computed tomography and magnetic resonance images (MRI) of the brain were unremarkable. He presented with ongoing headache and homonymous hemianopia. The follow-up brain MRI reveale...
متن کاملWhen should MELAS (Mitochondrial myopathy, Encephalopathy, Lactic Acidosis, and Stroke-like episodes) be the diagnosis?
Mitochondrial myopathy, Encephalopathy, Lactic Acidosis, and Stroke-like episodes (MELAS) is a rare mitochondrial disorder. Diagnostic criteria for MELAS include typical manifestations of the disease: stroke-like episodes, encephalopathy, evidence of mitochondrial dysfunction (laboratorial or histological) and known mitochondrial DNA gene mutations. Clinical features of MELAS are not necessaril...
متن کاملunilateral cortical thickening and hyper-intensity due to mitochondrial encephalopathy, lactic acidosis, and stroke like episodes (melas)
patients with mitochondrial encephalopathy, lactic acidosis and stroke-like episodes (melas) present with recurrent and partially reversible neurological deficits. lesions of melas classically cause a signal change in both the grey and white matter, predominantly in the occipital and parietal lobes. these lesions mimic infarction. here, we reported a case of melas with rare neuroimaging finding...
متن کاملImportance of Distinguishing Between Mitochondrial Encephalomyopathy With Elderly Onset of Stroke-Like Episodes and Cerebral Infarction
The most common disease-causing mitochondrial DNA (mtDNA) mutation in mitochondrial encephalomyopathy (ME) with lactic acidosis and stroke-like episodes (MELAS) is m.3243A>G. In the future, the incidence of patients with cerebral infarction and diabetes mellitus is expected to increase tremendously. Additionally, the A3243G mutation typical of diabetes is estimated to be present in approximatel...
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ژورنال
عنوان ژورنال: Wellcome Open Research
سال: 2019
ISSN: 2398-502X
DOI: 10.12688/wellcomeopenres.15599.1